PIBF1 Polyklonale Antilichaam, Cy5 Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
PIBF is synthesized during pregnancy in response to progesterone by progesterone receptor-positive T lymphocytes (mostly gamma-delta T cells) . In the presence of PIBF, natural killer (NK) cells inhibit the release of perforin from storage granules and therefore fail to lyse target cells. In humans, the amount of cells that express PIBF is significantly higher in healthy pregnant women than in women at risk for premature pregnancy termination. Full-length PIBF is associated with the nucleus, whereas secretion of shorter forms is induced by activation of the cell. Research suggests that PIBF functions as a transcription factor in its full-length form, while smaller forms may act as cytokines. The PIBF gene encodes a deduced hydrophilic 757-amino acid alpha-helical protein with an N-terminal signal sequence, a leucine zipper motif, a basic zipper sequence, a PEST sequence, a nuclear localization signal, an endoplasmic reticulum membrane retention signal, and many presumeed N-glycosylation and phosphorylation sites.
PIBF 1; PIBF; PIBF1; PIBF-1; Progesterone immunomodulatory binding factor 1; Progesterone induced blocking factor 1; Progesterone-Induced Blocking Factor 1; RP11 505F3.1; PIBF1_HUMAN; C13orf24.
10464
• Rabbit
Human, Mouse, Rat
551-651/757
PIBF1
• Polyclonal
• IgG
Cy5
KLH conjugated synthetic peptide derived from human PIBF1/C13orf24
IF
Purified by Protein A.
625,650nm/670nm
1µg/µl
IF (IF=1:100-500)
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
10464
Beschrijving
PIBF1 Polyklonale Antilichaam, Cy5 Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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