PIG3 (TP53I3) Mouse Monoclonal Antibody [Kloon ID: LBI3B11]

The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) TP53I3 mouse monoclonal antibody, clone LBI3B11

PIG3

Homo sapiens tumor protein p53 inducible protein 3 (TP53I3), transcript variant 2, mRNA.

9540

Q53FA7

Unconjugated

P53 signaling pathway

P53 signaling pathway

WB 1:2000, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

TP53I3

https://www.ncbi.nlm.nih.gov/gene/?term=9540

https://www.uniprot.org/uniprot/Q53FA7