PIGP Antilichaam

This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI) -anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI) . This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. This gene has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family. Alternatively spliced transcript variants encoding different isoforms have been described.

51227

P57054

Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 25-158 of human PIGP (NP_710148.1) .

Unconjugated

Primary Antibodies

Other

Affinity purification

Mouse brain

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 22kDa

IgG

WB: 1:200 - 1:2000

PIGP

Phosphatidylinositol glycan anchor biosynthesis class P

Homo sapiens

DCRC, DCRC-S, DSCR5, DSRC, EIEE55, PIG-P, phosphatidylinositol N-acetylglucosaminyltransferase subunit P, Down syndrome critical region gene 5, Down syndrome critical region protein 5, Down syndrome critical region protein C, phosphatidylinositol glycan, class P, phosphatidylinositol-glycan biosynthesis class P protein, phosphatidylinositol-n-acetylglucosaminyltranferase subunit

WB

Liquid