PIK3CB Antilichaam - C-terminal regio : HRP (ARP32117_T100-HRP)

Phosphoinositide-3-kinase, catalytic, beta polypeptide

PI3K, PIK3C1, P110BETA, PI3KBETA

5291

Q24JU2

NP_006210

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human PIK3CB

Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. They have been implicated as participants in signaling pathways regulating cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kD catalytic subunit, such as PIK3CB, and an 85-kD adaptor subunit (Hu et al., 1993) .[supplied by OMIM].

EGFR; IRS1; GRB2; PIK3R1; GAB2; PIK3R2; CRK; CBL; RAB5A; UBC; ALAS1; HPS6; DVL3; ALK; AGTR2; PRKCD; PRKCE; YWHAQ; HCK; MME

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

123kDa

Zhao, J.J., et al., (2005) Proc. Natl. Acad. Sci. U.S.A. 102 (51), 18443-18448

Wet Ice

1070

PIK3CB

PIK3CB

Rabbit

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

NM_006219

VKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKD

Beta isoform