PIM-35

PIM-35 is a derivative of Indole. PIM-35 significantly inhibits serotonin (5HT) and dopamine (DA) uptake with a weak inhibitory effect on noradrenaline (NA) uptake.PIM-35 has antidepressant activity and can be used for depression research[1].

130445-55-5

12352005

H302-H319

5-HT Receptor; Adrenergic Receptor; Dopamine Receptor; Drug Derivative

GPCR/G Protein; Neuronal Signaling; Others

Neurological Disease

COC1=CC2=C(C=C1)NC(=C2)CN

C10H12N2O

176.22

P264-P270-P280-P330-P501

[1]Carranza Gómez-Carpintero MC, et al. Involvement of the serotonergic system in the mode of action of the new potential antidepressant agent 5-methoxyindolyl-2-methylamine. Arzneimittelforschung. 1993 Aug;43 (8) :809-13.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W284026/

Reference compound2

No Development Reported