PIM1 Antilichaam - N-terminaal gebied: Biotine (ARP56390 P050-Biotine)
Gecertificeerd

PIM1 Antilichaam - N-terminaal gebied: Biotine (ARP56390 P050-Biotine)

Catalog #: ARP56390_P050-Biotin
Maat: 100 µL

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Gene Name

Pim-1 oncogene

Gene Aliases

PIM

Gene ID

5292

Swiss Prot

P11309-2

Accession Number

NP_002639

Host

• Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PIM1

Target

PIM1 may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. Isoform 2 promotes the G1/S transition of the cell cycle via up-regulation of CDK2 activity and phosphorylation of CDKN1B, resulting in enhanced nuclear export and

Partner Proteins

FXR2; NHLH1; FH; BEND7; HEXIM2; BANP; TFPT; ZBTB1; UBC; APP; MARK3; HSP90AA1; HSPA4; PIM1; MDM2; ELAVL1; FZR1; SKP2; PPP2R5E; PPP2R4; PPP2CA; PIN1; CDC34; CDC20; ABCB1; HIST2H3C; MYC; MAX; SNX6; CBX1; CBX3; BAD; HIST3H3; SND1; PTPRO; NFATC1; SHMT1; EPHA3

Clonality

• Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

PIM1 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Wernig, G., (2008) Blood 111 (7), 3751-3759

Shipping Conditions

Wet Ice

Protein Length

404

NCBI Gene Symbol

PIM1

NCBI GB Accession Number

PIM1

Host or Source

Rabbit

Protein Name

Serine/threonine-protein kinase pim-1

Nucleotide Accession Number

NM_002648

Peptide Sequence

MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFG

Beschrijving

PIM1 Antilichaam - N-terminaal gebied: Biotine (ARP56390 P050-Biotine) Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamPIM1 Antilichaam - N-terminaal gebied: Biotine (ARP56390 P050-Biotine)
Categorie
Beschikbare grootte100 µL
CatalogusnummerARP56390_P050-Biotin