PIN1 Antilichaam

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.

5300

Q13526

Human, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-163 of human PIN1 (NP_006212.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Neuroscience

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 17kDa

IgG

PIN1

Jurkat

Peptidylprolyl cis/trans isomerase, NIMA-interacting 1

Homo sapiens

PIN1, protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1, DOD, UBL5, peptidyl-prolyl cis/trans isomerase, NIMA-interacting, prolyl isomerase, protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1

WB, IF

Liquid