Pioglitazon HCl
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
112529-15-4
AD-4833, U-72107E
C08234-10mg
P450 (e.g. CYP17)
Metabolism
CCC1=CN=C (C=C1) CCOC2=CC=C (C=C2) CC3C (=O) NC (=O) S3.Cl
C19H20N2O3S.HCl
Pioglitazone HCl (AD-4833, U-72107E) is an inhibitor of cytochrome P450 (CYP) 2C8 and CYP3A4 enzymes. Pioglitazone HCl inhibits CYP2C8, CYP3A4 and CYP2C9 with Ki of 1.7 μM, 11.8 μM and 32.1 μM, respectively. Pioglitazone HCl is also a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist with EC50 of 0.93 μM and 0.99 μM for human PPARγ and mouse PPARγ, respectively. Pioglitazone HCl inhibits mitochondrial iron uptake, lipid peroxidation, and subsequent ferroptosis.
2 years -80 in solvent
Beschrijving
Pioglitazon HCl Beschikbaar in 10 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
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