Pipcroside B

Pipcroside B is found in P. crocatum Ruiz & Pav. Pipcroside B is a PDH inhibitor (IC50: 99.82 µM) . Pipcroside B has antibacterial activity and is used in the study of oral infections[1][2][3].

12352211

Bacterial; PDHK

Anti-infection; Metabolic Enzyme/Protease

COVID-19-immunoregulation

Infection

C[C@@H]([C@@]([C@H]1O)(C=C(C2=O)OC)CC=C)[C@@H](C3=CC(OC)=C(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)C(OC)=C3)[C@]12OC

C28H38O12

566.59

[1]Li HX, et al. Isolation of Two New Compounds and Other Constituents from Leaves of Piper crocatum and Study of Their Soluble Epoxide Hydrolase Activities. Molecules. 2019 Jan 30;24 (3) :489.|[2]Chai YJ, et al. Unusual Bicyclo[3.2.1]Octanoid Neolignans from Leaves of Piper crocatum and Their Effect on Pyruvate Dehydrogenase Activity. Plants (Basel) . 2021 Sep 7;10 (9) :1855.|[3]Kurnia D, et al. Anti-Infection of Oral Microorganisms from Herbal Medicine of Piper crocatum Ruiz & Pav. Drug Des Devel Ther. 2024 Jun 25;18:2531-2553.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N15517/

Natural Products

No Development Reported