PIR Antilichaam - C-terminaal gebied: Biotine (ARP33665 T100-Biotine)

Pirin (iron-binding nuclear protein)

8544

O00625

NP_003653

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human PIR

PIR is a member of the cupin superfamily. The protein is an Fe (II) -containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication.This gene encodes a member of the cupin superfamily. The encoded protein is an Fe (II) -containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.

SMAD9; UBL7; SPEN; SUGT1; STAM; PSMB2; PPP2CA; CLNS1A; ARHGDIA; NFIX; NFKBIA; BCL3

Biotin

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 86%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

32kDa

Adams, M. (2005) J. Biol. Chem. 280 (31), 28675-28682

Wet Ice

290

PIR

PIR

Rabbit

Pirin

NM_003662

EPHHTAVLGEGDSVQVENKDPKRSHFVLIAGEPLREPVIQHGPFVMNTNE