Pirocton
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Piroctone is a potent hydroxypyridone antimicrobial agent that shows remarkable activity against fungi including Candida species. Piroctone inhibits hyphal induction of Candida albicans. Piroctone can efficiently chelate intracellular iron to induce relevant cytotoxicity in neuroblastoma cells. Piroctone can be used for antimicrobial and neuroblastoma research[1][2].
50650-76-5
12352005
Fungal
Anti-infection
Cancer; Infection
O=C1C=C(C)C=C(CC(CC(C)(C)C)C)N1O
C14H23NO2
237.34
[1]Sigle HC, et al. In vitro investigations on the mode of action of the hydroxypyridone antimycotics rilopirox and piroctone on Candida albicans. Mycoses. 2006 May;49 (3) :159-68.|[2]Sidarovich V, et al. Translational downregulation of HSP90 expression by iron chelators in neuroblastoma cells. Mol Pharmacol. 2015;87 (3) :513-24.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-180521/
Reference compound1
No Development Reported
Beschrijving
Piroctone is a potent hydroxypyridone antimicrobial agent that shows remarkable activity against fungi including Candida species. Piroctone inhibits hyphal indu
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