PLA2G10 Antilichaam

This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism.

8399

O15496

Human

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PLA2G10 (NP_003552.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Signal Transduction

Affinity purification

K-562

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 18kDa

IgG

WB: 1:500 - 1:2000

PLA2G10

Phospholipase A2 group X

Homo sapiens

GXPLA2, GXSPLA2, SPLA2, sPLA2-X, group 10 secretory phospholipase A2, group X secretory phospholipase A2, phosphatidylcholine 2-acylhydrolase 10

WB

Liquid