PLA2R1 Antilichaam / Fosfolipase A2 receptor 1

Receptor for secretory phospholipase A2 (sPLA2) . Acts as a receptor for phospholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. [UniProt]

Immunohistochemistry (FFPE) : 1-2 µg/mL

Q13018

Human

A portion of amino acids 300-600 from human PLA2R1 protein was used as the immunogen for the PLA2R1 antibody.

PLA2R1/4893

IHC-P

Protein A affinity

Purified

This PLA2R1 antibody is available for research use only.

Aliquot the PLA2R1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

1 mg/mL in 1X PBS; BSA free, sodium azide free

Optimal dilution of the PLA2R1 antibody should be determined by the researcher.

Cell membrane, Secreted

IHC staining of FFPE human kidney tissue with PLA2R1 antibody (clone PLA2R1/4893) . Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.