PLA2R1 Antilichaam / Fosfolipase A2 receptor 1

Receptor for secretory phospholipase A2 (sPLA2) . Acts as a receptor for phospholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. [UniProt]

Immunohistochemistry (FFPE) : 1-2 µg/mL

Q13018

Human

A portion of amino acids 300-600 from human PLA2R1 protein was used as the immunogen for the PLA2R1 antibody.

PLA2R1/4893

IHC-P

Protein A affinity

Purified

This PLA2R1 antibody is available for research use only.

Aliquot the PLA2R1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Optimal dilution of the PLA2R1 antibody should be determined by the researcher.

Cell membrane, Secreted

IHC staining of FFPE human kidney tissue with PLA2R1 antibody (clone PLA2R1/4893) . Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.