PLA2R1 Antilichaam / Fosfolipase A2 receptor 1

This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.

Immunohistochemistry (FFPE) : 1-2 µg/mL

Q13018

Human

A portion of amino acids 300-600 from human PLA2R1 protein was used as the immunogen for the PLA2R1 antibody.

PLA2R1/4891

IHC-P

Protein G affinity

Purified

This PLA2R1 antibody is available for research use only.

Aliquot the PLA2R1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Optimal dilution of the PLA2R1 antibody should be determined by the researcher.

Cell membrane, Secreted

IHC staining of FFPE human kidney tissue with PLA2R1 antibody (clone PLA2R1/4891) . Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.