PLD1 (fosfo Thr147) Antilichaam

Phosphatidylcholine (PC) -specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis.

5337

Q13393

NP_002653.1

Human, Mouse, Rat

PLD1 (phospho Thr147) antibody was raised against a peptide sequence around phosphorylation site of threonine 147 (R-H-T (p) -F-R) derived from Human PLD1.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

120 kDa

IgG

The antibody detects endogenous levels of PLD1 only when phosphorylated at threonine 147.

Western Blot: 1:500~1:1000

PLD1

Phospholipase D1, phosphatidylcholine-specific

Homo sapiens

Hammond S.M., J. Biol. Chem. 272:3860-3868 (1997) [PubMed: 9013646].

Steed P.M., FASEB J. 12:1309-1317 (1998) [PubMed: 9761774].

Lopez I., J. Biol. Chem. 273:12846-12852 (1998) [PubMed: 9582313].

PLD 1, hPLD1, Choline phosphatase 1

WB

4505873

Liquid