PLD2 (fosfo-Tyr169) Antilichaam

Phosphatidylcholine (PC) -specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.

5338

O14939

NP_002654.3

Human, Mouse, Rat

PLD2 (phospho Tyr169) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 169 (E-N-Y (p) -L-N) derived from Human PLD2.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

95 kDa

IgG

The antibody detects endogenous levels of PLD2 only when phosphorylated at tyrosine 169.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

PLD2

Phospholipase D2

Homo sapiens

Steed P.M., FASEB J. 12:1309-1317 (1998) .

Lopez I., J. Biol. Chem. 273:12846-12852 (1998) .

Divecha N., EMBO J. 19:5440-5449 (2000) .

PLD 2, PLD1C, choline phosphatase 2

WB, IHC

156564407

Liquid