Pleigonadotrofine

Human Pleiotrophin (PTN) also called HARP (Heparin affin-regulatory peptide) is a new member of the heparin-binding neurotrophic factor family. PTN and Midkine are structural homologs, and are highly conserved among species. PTN plays an important role in development processes and promotion of neurite extension. Recombinant Pleiotrophin is a 15.4 kDa protein consisting of 136 amino acid residues.

PTN; HARP; HBNF; HBGF8; NEGF1

5764

P21246

NP_002816.1

NM_002825

7q33

Human

Mouse, Rat, Human, Chicken, Hamster, Bacteria

GKKEKPEKKV KKSDCGEWQW SVCVPTSGDC GLGTREGTRT GAECKQTMKT QRCKIPCNWK KQFGAECKYQ FQAWGECDLN TALKTRTGSL KRALHNAECQ KTVTISKPCG KLTKPKPQAE SKKKKKEGKK QEKMLD

Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

< 0.1 ng/µg of protein (< 1EU/µg)

> 98% by SDS-PAGE & HPLC analyses

Data not available.

136

Lyophilized

Water

15.4 kDa

The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.

E. coli