PlGF-3
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
PlGF-3 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-3 is expressed exclusively in the placenta. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. PlGF-3 lacks heparin binding affinity. Recombinant human PlGF-3 is a 45.7 kDa disulfide-linked homodimeric protein of two 203 amino acid polypeptide chains.
PlGF; placental growth factor
5228
P49763-1
NP_001193941.1
NM_001207012.1
2p21-p16
Human
Human
LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRHSPGRQS PDMPGDFRAD APSFLPPRRS LPMLFRMEWG CALTGSQSAV WPSSPVPEEI PRMHPGRNGK KQQRKPLREK MKPERCGDAV PRR
< 0.1 ng/µg of protein (< 1EU/µg)
> 95% by SDS-PAGE & HPLC analyses
Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-50.0 ng/ml.
203
Lyophilized
45,7 kDa
E. coli
Beschrijving
PlGF-3 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-3 is expressed exclusively in the placenta. It signals thro
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