PLX51107
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1627929-55-8
C18221-2mg
Epigenetic Reader Domain
Epigenetics
CC1=C (C (=NO1) C) C2=CC3=C (C (=CN3C (C) C4=CC=CC=N4) C5=CC=C (C=C5) C (=O) O) N=C2
C26H22N4O3
PLX51107 is as a novel BET inhibitor with modest preference for bromodomain-1 (BD1) versus bromodomain-2 (BD2) within each BET protein (Kd = 1.6, 2.1, 1.7, and 5 nM for BD1 and 5.9, 6.2, 6.1 and 120 nM for BD2 of BRD2, BRD3, BRD4, and BRDT, respectively. Among non-BET proteins, PLX51107 shows significant interactions only with the bromodomains of CBP and EP300 (p300) (Kd in the 100 nM range) .
3 years -20°C powder
Beschrijving
PLX51107 Beschikbaar in 2 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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