PMS1 Antilichaam

This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

5378

P54277

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 405-619 of human PMS1 (NP_000525.1) .

Unconjugated

Primary Antibodies

Other

Affinity purification

Mouse liver

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 110kDa

IgG

WB: 1:500 - 1:2000

PMS1

Mouse spleen

Rat brain

PMS1 postmeiotic segregation increased 1 (S. cerevisiae)

Homo sapiens

PMS1, PMS1 postmeiotic segregation increased 1 (S. cerevisiae), PMSL1, hPMS1, HNPCC3, postmeiotic segregation 1, human homolog of yeast mutL, MLH1

WB

Liquid