PMS2 Mouse Monoclonal Antibody [Kloon ID: LBI4B7]

This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) PMS2 mouse monoclonal antibody, clone LBI4B7

HNPCC4; PMS2CL; PMSL2

Homo sapiens PMS1 homolog 2, mismatch repair system component (PMS2), transcript variant 1, mRNA.

5395

P54278

Unconjugated

Mismatch repair

Mismatch repair

WB 1:500, IHC 1:150, IF: 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

PMS2

https://www.ncbi.nlm.nih.gov/gene/?term=5395

https://www.uniprot.org/uniprot/P54278