Pneumocandin A1

Pneumocandin A1 is a lipopeptide antibiotic. Pneumocandin A1 has a strong anti-Candida effect. Pneumocandin A1 has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL[1].

135862-90-7

12352211

Antibiotic; Bacterial

Anti-infection

Infection

CC[C@@H](C[C@@H](CCCCCCCCC(N[C@@H]1C[C@@H](O)[C@@H](O)NC([C@@H]2[C@@H](O)[C@@H](C)CN2C([C@H]([C@H](O)CC(N)=O)NC([C@H](C[C@@H](O)C3=CC=C(O)C=C3)NC([C@@H]4C[C@@H](O)CN4C([C@H]([C@H](O)C)NC1=O)=O)=O)=O)=O)=O)=O)C)C

C51H82N8O16

1063.24

[1]Jean-Francois Timsit, et al. Empirical Micafungin Treatment and Survival Without Invasive Fungal Infection in Adults With ICU-Acquired Sepsis, Candida Colonization, and Multiple Organ Failure: The EMPIRICUS Randomized Clinical Trial. JAMA. 2016 Oct 18;316 (15) :1555-1564.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N14464/

Natural Products

No Development Reported