PNP Antilichaam

This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.

4860

P00491

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human PNP (NP_000261.2) .

Unconjugated

Primary Antibodies

Neuroscience

Affinity purification

NCI-H460

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 32kDa

IgG

PNP

Mouse liver

Purine nucleoside phosphorylase

Homo sapiens

NP, MGC117396, MGC125915, MGC125916, PNP, PRO1837, PUNP, NP

WB, IF

Liquid