POLG Antilichaam / DNA polymerase subeenheid gamma 1

Mutations in POLG are associated with a range of mitochondrial disorders, including progressive external ophthalmoplegia, Alpers-Huttenlocher syndrome, and ataxia-neuropathy syndromes. Studying POLG function helps researchers understand mitochondrial genome maintenance and the molecular basis of mitochondrial diseases. Using a high-quality POLG antibody allows for sensitive detection of the protein in assays such as western blot, immunohistochemistry, and immunofluorescence. A POLG antibody from NSJ Bioreagents offers consistent performance, supporting studies in mitochondrial biology, genetic disorders, and DNA repair mechanisms. Choosing the right POLG antibody is critical for producing reliable and reproducible research results.

Western blot: 1:500-1:2000

P54098

Human

A peptide sequence specific to DNA polymerase subunit gamma 1 was used as the immunogen for the POLG antibody.

24P93

WB

Affinity chromatography

Purified

This POLG antibody is available for research use only.

After reconstitution, the POLG antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Optimal dilution of the POLG antibody should be determined by the researcher.

Western blot testing of human 1) MCF7, 2) Jurkat and 3) SiHa cell lysate with POLG antibody. Predicted molecular weight ~140 kDa.