Pomalidomide 7'OMe
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Pomalidomide 7'OMe is a E3 ligase ligand that can be used in the recruitment of CRBN protein. Pomalidomide 7'OMe can be connected to the BRD9 ligand by a linker to synthesis of PROTAC BRD9 degrader-9 (HY-177729).
2154355-10-7
12352005
H302-H315-H319-H335
Ligands for E3 Ligase
PROTAC
Cancer
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C(OC)=CC=C3N)=O
C14H13N3O5
303.27
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
[1]Bouguenina H, et al. A Degron Blocking Strategy Towards Improved CRL4CRBN Recruiting PROTAC Selectivity. Chembiochem. 2023 Dec 1;24 (23) :e202300351.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W877239/
Reference compound1
No Development Reported
Cereblon
Beschrijving
Pomalidomide 7'OMe is a E3 ligase ligand that can be used in the recruitment of CRBN protein. Pomalidomide 7'OMe can be connected to the BRD9 ligand by a linker
Specificaties
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MS Solution sufficient for 400 Mini, 142 Midi, 33 Maxi
MS10
Each
MS pipette, variable vol µme 10~100 µL
MSP-100
1 Unit
MS 12-ch pipette, variable vol µme 20~200 µL
MSP-12X200
1 Unit
MS 12-ch pipette, variable vol µme 2~20 µL
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1 Unit
MS Rocking anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRK-3001
1 Unit
MS Orbital Shaker with 30 x 30 cm platform and flat non-slip rubber mat
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1 Unit
MS Reciprocal anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
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1 Unit
MS pipette, variable vol µme 1000~10000 µL
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1 Unit