POT1 Antilichaam

This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

25913

Q9NUX5

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 497-634 of human POT1 (NP_056265.2) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

Affinity purification

A-431

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 75kDa

IgG

POT1

HeLa

DU145

Mouse liver

Protection of telomeres 1

Homo sapiens

CMM1GLM9, HPOT1, protection of telomeres protein 1, POT1-like telomere end-binding protein, protection of telomeres 1 homolog

WB, IHC

Liquid