POT1 Antilichaam - middengebied: Biotine (ARP58317_P050-Biotine)

Protection of telomeres 1 homolog (S. pombe)

GLM9, CMM10, HPOT1

25913

Q9NUX5

NP_056265

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human POT1

This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

TPP1; CFL2; ACD; CORO1A; KHDRBS1; LAMC3; BCAS2; MVP; ZNF32; ECI1; CSNK2B; COX6A2; ALDH1A1; ACTN4; SERTAD1; C2orf74; ZBTB49; ZBED2; CYP4F11; MYO5C; RIF1; NAP1L1; MDM2; KRT18; GRN; PACSIN1; SULT4A1; PGLS; AIPL1; SH3BP1; HAAO; NCDN; TWF2; ACOT7; DDX19B; PACS

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

70kDa

Wet Ice

634

POT1

POT1

Rabbit

Protection of telomeres protein 1

NM_015450

MNSENQTMLSLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLESANLTAN