PPAR-alfa (PPARA) Mouse Monoclonal Antibody [Kloon ID: LBI2F3]

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) PPARA mouse monoclonal antibody, clone LBI2F3

HPPAR; NR1C1; PPAR; PPAR-alpha; PPARalpha

Homo sapiens peroxisome proliferator activated receptor alpha (PPARA), transcript variant 5, mRNA.

5465

Q07869

Unconjugated

Adipocytokine signaling pathway, PPAR signaling pathway

Adipocytokine signaling pathway, PPAR signaling pathway

WB 1:500, IF 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

PPARA

https://www.ncbi.nlm.nih.gov/gene/?term=5465

https://www.uniprot.org/uniprot/Q07869