PPFIBP1 Antilichaam

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

8496

Q86W92

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 846-1005 of human PPFIBP1 (NP_003613.3) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

A-375

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 114kDa

IgG

PPFIBP1

HeLa

Mouse liver

PTPRF interacting protein, binding protein 1 (liprin beta 1)

Homo sapiens

PPFIBP1, L2, hSGT2, hSgt2p, SGT2

WB, IF

Liquid