PPP1R13B Antilichaam - middelste regio : HRP (ARP47979_P050-HRP)

Protein phosphatase 1, regulatory subunit 13B

P85, ASPP1, p53BP2-like

23368

Q96KQ4

NP_056131

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human PPP1R13B

PPP1R13B is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.

TRAF1; CCDC184; MIPOL1; LATS2; SIAH2; PPP1CC; PPP1CA; HRAS; LATS1; KHDRBS1; ERBB2; CEP63; TNIK; CDC5L; UBC; PLEKHA5; APC; TP63; TP73; E2F4; E2F3; E2F2; E2F1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

PPP1R13B is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

119kDa

Agirre, X., (2006) Oncogene 25 (13), 1862-1870

Wet Ice

1090

PPP1R13B

PPP1R13B

Rabbit

Apoptosis-stimulating of p53 protein 1

NM_015316

EFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNA