PPP2R4 Antilichaam

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

5524

Q15257

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 52-230 of human PPP2R4 (NP_821067.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction

Affinity purification

LO2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 40kDa

IgG

WB: 1:500 - 1:2000

PPP2R4

K-562

U-87MG

MCF7

Mouse brain

Rat brain

Protein phosphatase 2A activator, regulatory subunit 4

Homo sapiens

PPP2R4, protein phosphatase 2A activator, regulatory subunit 4, MGC2184, PP2A, PR53, PTPA, OTTHUMP00000022333, PP2A phosphatase activator, subunit B', phosphotyrosyl phosphatase activator, protein phosphatase 2A, regulatory subunit B', regulatory subunit B' (PR 53)

WB

Liquid