PPP4R2 Antilichaam - C-terminaal gebied: Biotine (ARP42719 P050-Biotine)

Protein phosphatase 4, regulatory subunit 2

PP4R2

151987

Q9NY27

NP_777567

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human PPP4R2

PPP4R2 is the regulatory subunit of serine/threonine-protein phosphatase 4 (PP4) . It may regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.

UBC; PAAF1; SMEK1; SF3A1; CCDC6; VASP; CCT3; PSMA1; INPPL1; AMPD2; LRRC47; DSTN; PLIN3; NUBP2; TPM1; TRA2B; IGBP1; CLNS1A; PPP4C; SRRM2; TIPRL; SMEK2; GEMIN4; DDX20

Biotin

Polyclonal Antibody

WB

Affinity Purified

PPP4R2 is supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

47kDa

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Wet Ice

417

PPP4R2

PPP4R2

Rabbit

Serine/threonine-protein phosphatase 4 regulatory subunit 2

NM_174907

DSRCTRQHCTEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNE

2