PQBP1 Antilichaam - middengebied: HRP (ARP31454_T100-HRP)

Polyglutamine binding protein 1

SHS, MRX2, MRX55, MRXS3, MRXS8, NPW38, RENS1

10084

O60828-5

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human PQBP1

This gene encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked cognitive disability. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

MAPRE1; GOLGA2; LZTS2; UBC; APBB1; WDR77; AQR; HNRNPH2; MRPL53; SLIRP; SRPRB; SUGP1; MRPS28; RPS6KA6; HRSP12; SCO2; ZC3H11A; UBL4A; VDAC3; RRBP1; RPS28; RBMS1; NDUFA7; IDH3G; APP; WBP11; RCVRN; LNX1; SF3A2; SFTPC; TXNL4A; TLX3; LRIF1; MED31; POLR2A; C14or

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

0.5 mg/ml

Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Rat: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

30kDa

Waragai, M. et al., (1999) Hum Mol Genet. 8 (6) :977-87

Wet Ice

265

PQBP1

PQBP1

Rabbit

Polyglutamine-binding protein 1

PSCGLPYYWNADREEGKERRHHRREELAPYPKSKKAVSRKDEELDPMDPS