Prealbumine (TTR) (NM 000371) Humaan Recombinant eiwit

This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017]

Purified recombinant protein of Human transthyretin (TTR), Gly21-End, Tag Free, expressed in E. coli, 50ug

ATTR; CTS; CTS1; HEL111; HsT2651; PALB; TBPA; TTN

7276

P02766, E9KL36

NM_000371

18q12.1

E. coli

Tag Free

>50ug/ml as determined by microplate BCA method

> 99% as determined by SDS-PAGE and Coomassie blue staining

Liquid

1 x PBS, pH7.4, 10% glycerol.

ES Cell Differentiation/IPS, Secreted Protein

16 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

TTR

Human

NP_000362

https://www.ncbi.nlm.nih.gov/gene/7276

https://www.uniprot.org/uniprot/P02766

https://www.ncbi.nlm.nih.gov/nuccore/NM_000371

https://www.ncbi.nlm.nih.gov/nuccore/NP_000362