Pregn-5-een-3β-ol

Pregn-5-en-3β-ol, a steroid compound, when formulated as the biscarboxylic acid hemiesters along with androst-5-en-3β-ol, serves as a potent positive allosteric modulator of NMDA (N-methyl-D-aspartate) receptors, making it applicable for research into psychiatric disorders[1].

2862-58-0

12352211

H302, H315, H319, H335

IGluR

Membrane Transporter/Ion Channel; Neuronal Signaling

Neurological Disease

97.0

C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)([C@H](CC4)CC)C

C21H34O

302.49

H302, H315, H319, H335

[1]Marika Matousova, et al. Pregn-5-en-3β-ol and androst-5-en-3β-ol dicarboxylic acid esters as potential therapeutics for NMDA hypofunction: In vitro safety assessment and plasma stability. Steroids. 2019 Jul:147:4-9.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-W882667/Pregn-5-en-3β-ol-SDS-MedChemExpress.pdf

Reference compound1

No Development Reported