Preladenant
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Preladenant is a potent (Ki = 1.1nM) and selective (>1000-fold over other adenosine receptors) adenosine A2A antagonist.1 It has shown efficacy in rodent and primate models of Parkinsons disease without inducing dyskinesias and displays antidepressant effects.1-3 It has been shown that activation of the adenosine A2A receptor blocks the activation of immune cells and increases the number of regulatory T-cells.4-6 Currently in clinical trials as combination therapy with pembrolizumab.7
Unconjugated
Beige solid
-20°C
Beschrijving
Preladenant Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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