Prioneiwit (118-135), humaan

Prion Protein (118-135), human is the 118-135 fragment of human prion protein. Prion Protein (118-135), human induces Apoptosis. Prion Protein (118-135), human stimulates caspase-3 and -9 activities. Prion Protein (118-135), human is cytotoxic to retinal neurons. Prion Protein (118-135), human exerts neurotoxic effects[1].

202121-03-7

12352209

Apoptosis; Caspase

Apoptosis

Neurological Disease

O=C(NCC(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(NCC(NCC(N[C@@H](CC(C)C)C(NCC(NCC(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CCSC)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CCSC)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

C68H112N18O22S2

1597.85

[1]Chabry J, et al. In vivo and in vitro neurotoxicity of the human prion protein (PrP) fragment P118-135 independently of PrP expression. J Neurosci. 2003 Jan 15;23 (2) :462-9.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11409/

Peptides

No Development Reported

Caspase 3; Caspase 9