PRKAA1 Antilichaam

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK) . AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

5562

Q13131

Human, Mouse, Rat

Recombinant protein of human PRKAA1

Unconjugated

Primary Antibodies

Apoptosis, Autophagy, Cancer, Cell Cycle, Neuroscience, Signal Transduction

Affinity purification

MCF7

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 65kDa

IgG

PRKAA1

Rat liver

Protein kinase, AMP-activated, alpha 1 catalytic subunit

Homo sapiens

PRKAA1, AMPK, AMPKa1, MGC33776, MGC57364

WB, IHC

Liquid