PRL / Prolactine Proteïne (Zijn label)

Prolactin (PRL) is a hormone with multiple actions in the central nervous system (CNS) spanning from physiology to pathology. PRL exerts different actions through its receptors that can be found in both neurons and glial cells (astrocytes, microglia and oligodendrocytes) of the brain. It is generally believed that in vertebrates, prolactin (PRL) is predominantly synthesized and released by pituitary lactotrophs and plays important roles in many physiological processes via activation of PRL receptor (PRLR), including water and electrolyte balance, reproduction, growth and development, metabolism, immuno-modulation, and behavior.

Gha1 Protein; Prl Protein; Prl1a1 Protein

NP_035294.2

Mouse

Mouse

His-Tag

See Datasheet send with the product

< 1.0 EU per μg of the protein as determined by the LAL method

≥ 92 % as determined by SDS-PAGE.≥ 90 % as determined by SEC-HPLC.

Measured by its ability to induce PRL pathway activation in a Luciferase receptor Assay System. The ED50 for this effect is typically 50-500 ng/mL.

207

Lyophilized or frozen liquid

20 mM Tris, 300 mM NaCl, 10% Glycerol, pH 7.5.

See Datasheet

26 kDa

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Insect cells