PRLR Antilichaam

This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.

5618

P16471

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 25-234 of human PRLR (NP_000940.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle, Growth Factors, Signal Transduction

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 70kDa

IgG

WB: 1:1000 - 1:2000

PRLR

MCF7

Mouse ovary

Prolactin receptor

Homo sapiens

PRLR, HPRL receptor, PRL-R, HPRLrI, Prolactin receptor

WB

Liquid