PRMT1 Antilichaam

This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.

3276

Q99873

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 20-353 of human PRMT1 (NP_938074.2) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 42kDa

IgG

PRMT1

A549

Rat spleen

Rat lung

Rat brain

Protein arginine methyltransferase 1

Homo sapiens

PRMT1, ANM1, HCP1, IR1B4, HRMT1L2

WB, IF

Liquid