Probucol
Gecertificeerd

Probucol

Catalog #: bs-82555C-01
Maat: 1 g

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Background

Probucol (23288-49-5) is a unique antilipidemic drug which inhibits the oxidation of LDL cholesterol preventing the genesis of macrophage-derived foam cells and thus suppressing the formation of atherosclerotic vascular lesions.1 It inhibits ABCA1-mediated cholesterol efflux without influencing scavenger receptor (class B type 1) -mediated efflux.2 It enhances mitophagy and improves survival, locomotor function and dopaminergic neuron loss in zebrafish and fly models of mitochondrial damage.3 It attenuates NF-kB/NLRP3 signaling and augments Nrf-2-mediated antioxidant defense in nerve injury models.4 Improves learning and memory in aging mice.5 It protects neuronal cells against peroxide-induced damage and directly activates glutathione peroxidase-1.6

Conjugation

Unconjugated

Buffer

Off-white solid

Storage Conditions

RT

Beschrijving

Probucol Beschikbaar in 1 g. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamProbucol
Categorie
Beschikbare grootte1 g
Catalogusnummerbs-82555C-01