Procyanidine B2 3′-O-gallate

Procyanidin B2 3′-O-gallate (B2-3′-G), isolated from Rhodiola crenulata extracts, is a potent xanthine oxidase (XO) inhibitor (IC50 = 24.24 μM, Ki = 6.16 μM) . Procyanidin B2 3′-O-gallate has antioxidant activity and reduces the formation of UV-induced α-tocopheroxyl. Procyanidin B2 3′-O-gallate can be used for hyperuricemia and gout research[1][2].

73086-04-1

B2-3′-G; Epicatechin- (4β,8) -epicatechin gallate

12352005

Xanthine Oxidase

Metabolic Enzyme/Protease

Metabolism-protein/nucleotide metabolism

Inflammation/Immunology; Metabolic Disease

99.60

O[C@@H]1[C@@H](C2=C3C(C[C@H]([C@@H](C4=CC(O)=C(C=C4)O)O3)OC(C5=CC(O)=C(C(O)=C5)O)=O)=C(C=C2O)O)C6=C(O)C=C(O)C=C6O[C@@H]1C7=CC(O)=C(C=C7)O

C37H30O16

730.62

[1]Lourenço CF, et al. LDL isolated from plasma-loaded red wine procyanidins resist lipid oxidation and tocopherol depletion. J Agric Food Chem. 2008 May 28;56 (10) :3798-804.|[2]Chu YH, et al. Inhibition of xanthine oxidase by Rhodiola crenulata extracts and their phytochemicals. J Agric Food Chem. 2014 Apr 30;62 (17) :3742-9.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-N9783/Procyanidin-B2-3-O-gallate-SDS-MedChemExpress.pdf

Natural Products

No Development Reported