PROM1 Antilichaam

PROM1 is a pentaspan transmembrane glycoprotein that localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation (1) . Mutations in this gene have been shown to result in retinitis pigmentosa (2) . Expression of this gene is also associated with several types of cancer (3) .

8842

O43490

NP_006008

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Stem Cell, Cancer

PROM1 antibody is affinity chromatography purified via peptide column.

Cat. No. 1205 - Jurkat Cell Lysate

1 mg/mL

PROM1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

PROM1 antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.

IgG

PROM1 antibody is human, mouse and rat reactive. Multiple isoforms of PROM1 are known to exist.

PROM1

Cat. No. 17-005 - Jurkat Cell Slide

Prominin 1

Homo sapiens

Yin AH, Miraglia S, Zanjani ED, et al. AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood 1997; 90:5002-12.

Zhang Q, Zulfiqar F, Xiao X, et al. Severe retinitis pigmentosa mapped to 4p15 and associated with a novel mutation in the PROM1 gene. Hum. Genet. 2007; 122:293-9.

Tabu K, Bizen N, Taga T, et al. Gene regulation of Prominin-1 (CD133) in normal and cancerous tissues. Adv. Exp. Med. Biol. 2013; 777:73-85.

PROM1 Antibody: RP41, AC133, CD133, MCDR2, STGD4, CORD12, PROML1, MSTP061, Prominin-1, Antigen AC133

ELISA, WB, ICC, IF

5174387

Liquid