PROS1 Antilichaam

This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

5627

P07225

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 405-676 of human PROS1 (NP_000304.2) .

Unconjugated

Primary Antibodies

Other

Affinity purification

LO2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 75kDa

IgG

WB: 1:500 - 1:2000

PROS1

HeLa

293T

Mouse liver

Mouse kidney

Rat liver

Protein S

Homo sapiens

PROS, PS21, PS22, PS23, PS24, PS25, PSA, THPH5, THPH6, vitamin K-dependent protein S, protein S (alpha), protein Sa, vitamin K-dependent plasma protein S

WB

Liquid