Prostaatspecifiek Antigen (KLK3) Muismonoklonale Antilichaam [Kloon ID: LBI3A11]

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) KLK3 mouse monoclonal antibody, clone LBI3A11

APS; hK3; KLK2A1; PSA

Homo sapiens kallikrein related peptidase 3 (KLK3), transcript variant 1, mRNA.

354

P07288

Unconjugated

Pathways in cancer, Prostate cancer

Pathways in cancer, Prostate cancer

WB 1:2000, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Protease, Secreted Protein

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

KLK3

https://www.ncbi.nlm.nih.gov/gene/?term=354

https://www.uniprot.org/uniprot/P07288