PROZ Antilichaam

This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants.

8858

P22891

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 220-340 of human PROZ (NP_003882.1) .

Unconjugated

Primary Antibodies

Cell Cycle

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 48kDa

IgG

WB: 1:500 - 1:2000

PROZ

293T

Mouse kidney

Rat liver

Rat kidney

Protein Z, vitamin K-dependent plasma glycoprotein

Homo sapiens

PROZ, Vitamin K-dependent protein Z, Protein Z, PZ

WB

Liquid