PRR5 Antilichaam - C-terminaal gebied: Biotine (ARP56750_P050-Biotine)

Proline rich 5

PP610, PROTOR1, PROTOR-1, FLJ20185k

55615

P85299-4

NP_056181

Human

The immunogen is a synthetic peptide directed towards the C terminal region of human PRR5

This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.

MTOR; BRCA1; UBC; RICTOR; MAPKAP1; MLST8

Biotin

Polyclonal Antibody

WB

Affinity purified

0.5 mg/ml

Cow: 100%; Dog: 91%; Horse: 86%; Human: 100%; Pig: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

32 kDa

Guo, D., (2005) Biochem. Biophys. Res. Commun. 337 (4), 1308-1318

Wet Ice

293

PRR5

PRR5

Rabbit

Proline-rich protein 5

NM_001017528.2

SPAPHSGPCPSRLYPTTQPPEQGLDPTRSSLPRSSPENLVDQILESVDSD