PRTFDC1-eiwit, menselijk, recombinant (hij)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP) . The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis. PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse and has important implications for unraveling the molecular etiology of lesch-Nyhan disease (LND) . LND is a severe X-linked neurological disorder caused by a deficiency of hypoxanthine phosphoribosyltransferase. PRTFDC1 has a low, barely measurable phosphoribosyltransferase activity (in vitro) .
Ice Packs
-20°C
Beschrijving
PRTFDC1-eiwit, menselijk, recombinant (hij) Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.
Specificaties
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